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Proteintech
SSB Polyclonal Antibody
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Product Details
11720-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SSB Fusion Protein Ag2294 (1-408 aa encoded by BC001289)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAENGDNEK MAALEAKICH QIEYYFGDFN LPRDKFLKEQ IKLDEGWVPL EIMIKFNRLN RLTTDFNVIV EALSKSKAEL MEISEDKTKI RRSPSKPLPE VTDEYKNDVK NRSVYIKGFP TDATLDDIKE WLEDKGQVLN IQMRRTLHKA FKGSIFVVFD SIESAKKFVE TPGQKYKETD LLILFKDDYF AKKNEERKQN KVEAKLRAKQ EQEAKQKLEE DAEMKSLEEK IGCLLKFSGD LDDQTCREDL HILFSNHGEI KWIDFVRGAK EGIILFKEKA KEALGKAKDA NNGNLQLRNK EVTWEVLEGE VEKEALKKII EDQQESLNKW KSKGRRFKGK GKGNKAAQPG SGKGKVQFQG KKTKFASDDE HDEHDENGAT GPVKRAREET DKEEPASKQQ KTENGAGDQ (1-408 aa encoded by BC001289 )
Target Information
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: autoantigen La; La autoantigen; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; lupus La antigen; Lupus La protein; OTTHUMP00000204777; ribonucleoprotein La; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B; SS-B; SS-B/La protein; unnamed protein product
Gene Aliases: La; La/SSB; LARP3; SSB
UniProt ID: (Human) P05455
Entrez Gene ID: (Human) 6741
tRNA 5'-leader removal
RNA processing
tRNA modification
tRNA export from nucleus
tRNA processing
histone mRNA metabolic process
tRNA 3'-end processing
positive regulation of translation
nuclear histone mRNA catabolic process
IRES-dependent viral translational initiation
protein localization to cytoplasmic stress granule
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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