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Invitrogen
SSB Polyclonal Antibody
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FIGURE: 1 / 1
SSB Antibody (PA5-86082) in WB
Western blot analysis of SSB in Lane 1: HEK293T whole cell lysate (40 µg), Lane 2: L02 whole cell lysate (40 µg), Lane 3: SK-OVCAR3 whole cell lysate (40 µg), Lane 4: MCF-7 whole cell lysate (40 µg), Lane 5: HepG2 whole cell lysate (40 µg), Lane 6: A549 whole cell lysate (40 µg). Sample was incubated with SSB polyclonal antibody (Product # PA5-86082) using a 1:1000 dilution.
Product Details
PA5-86082
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 331-380 of Human SSB.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: autoantigen La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; lupus La antigen; Lupus La protein; Lupus La protein homolog; Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog); mRNA for autoantigen; OTTHUMP00000204777; ribonucleoprotein La; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B; SS-B; SS-B/La protein; unnamed protein product
Gene Aliases: La; La/SSB; LARP3; SS-B; SSB
UniProt ID: (Human) P05455, (Mouse) P32067
Entrez Gene ID: (Human) 6741, (Rat) 81783, (Mouse) 20823
tRNA 5'-leader removal
RNA processing
tRNA modification
tRNA export from nucleus
tRNA processing
histone mRNA metabolic process
tRNA 3'-end processing
positive regulation of translation
nuclear histone mRNA catabolic process
IRES-dependent viral translational initiation
protein localization to cytoplasmic stress granule
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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