FIGURE: 1 / 1
Immunogen sequence: TCTGYTDYDD YPPWTWDPTS REDLAKGTTT AGVPGHTLPW RTTRRPGSSS PAIRRLPDTG SKDGYKLPWT WDTPSGRGLA EGTPTAGKLG PTL
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 61%.
Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: scavenger receptor cysteine rich domain containing (5 domains); scavenger receptor cysteine rich family, 5 domains; scavenger receptor cysteine-rich glycoprotein; Soluble scavenger protein with 5 SRCR domains; Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D; soluble scavenger with 5 domains; SSc5D
Gene Aliases: S5D-SRCRB; SSC5D
UniProt ID: (Human) A1L4H1
Entrez Gene ID: (Human) 284297
Molecular Function: serine protease