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Product Details
PA5-120328
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 270-369 of human Somatostatin Receptor 2 (SSTR2) (NP_0010411)
Conjugate
Form
Liquid
Concentration
1.17 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913900
Product Specific Information
Positive test controls include: mouse kidney, mouse liver. The target is usually found in the following locations: Cell membrane, Cytoplasm, Multi-pass membrane protein.
Immunogen sequence: LPFYIFNVSS VSMAISPTPA LKGMFDFVVV LTYANSCANP ILYAFLSDNF KKSFQNVLCL VKVSGTDDGE RSDSKQDKSR LNETTETQRT LLNGDLQTSI
Target Information
SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in the cerebrum and kidney. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The receptor is coupled via pertussis toxin sensitive G proteins to inhibit adenylyl cyclase.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: somatostatin receptor; somatostatin receptor 2a; somatostatin receptor subtype 2; Somatostatin receptor type 2; somatotropin release-inhibiting factor receptor; SRIF-1; SS-2-R; SS2-R; SS2R; SSR2; SSTR2A
Gene Aliases: Smstr-2; Smstr2; Sst2; SSTR-2; SSTR2
UniProt ID: (Human) P30874, (Mouse) P30875, (Rat) P30680
Entrez Gene ID: (Human) 6752, (Mouse) 20606, (Rat) 54305
regulation of muscle contraction
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
spermatogenesis
response to nutrient
digestion
negative regulation of cell proliferation
cerebellum development
peristalsis
forebrain development
somatostatin signaling pathway
response to starvation
cellular response to glucocorticoid stimulus
cellular response to estradiol stimulus
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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