Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
PA3-209 detects SSTR5 in rat and mouse samples.
PA3-209 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures.
The PA3-209 immunogen is a synthetic peptide corresponding to the C-terminal amino acids Q(344)ATLPTRSCEANGLMQTSRI(363) of SSTR5
Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: somatostatin receptor; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS-5-R; SS5-R; SS5R
Gene Aliases: Smstr5; Somato; sst5; Sstr5
UniProt ID: (Mouse) O08858
Entrez Gene ID: (Rat) 25354, (Mouse) 20609
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