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Invitrogen
SSX2 Polyclonal Antibody
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Product Details
PA5-80074
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SSX2 (157-184aa NREAQEKEERRGTAHRWSSQNTHNIGRF).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: MCF-7 Cell, HELA Cell. IHC: Human Intestinal Cancer Tissue.
Target Information
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2; CT52; MGC119055; MGC15364; MGC3884; Protein SSX2; sarcoma, synovial, X-chromosome-related 2; SSX2; Synovial sarcoma, X breakpoint 2; synovial sarcoma, X breakpoint 2B; Tumor antigen HOM-MEL-40
Gene Aliases: CT5.2; CT5.2A; HD21; HOM-MEL-40; SSX; SSX2; SSX2A; SSX2B
UniProt ID: (Human) Q16385
Entrez Gene ID: (Human) 6757
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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