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Product Details
PA5-59190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ST3GAL1. Recombinant protein control fragment (Product #RP-89952).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647965
Product Specific Information
Immunogen sequence: MVLELSENLK RLIKHRPCTC THCIGQRKLS AWFDERFNQT MQPLLTAQNA LLEDDTYRWW LRLQREKKPN NLNDTIKELF RVVPGNVDPM LEKRSVGCRR CAVVGNSGNL RESSYGPEID SHDFVLRMNK APTAGFEA
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.
Target Information
ST3GAL1 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. It is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of ST3GAL1 protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B.The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Gal-NAc6S; MGC9183; Monosialoganglioside sialyltransferase; Sialyltransferase 4A; sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); SIAT4-A; SIATFL; ST3Gal I; ST3GalA.1; ST3GalI; ST3O
Gene Aliases: Gal-NAc6S; SIAT4; SIAT4A; SIATFL; ST3GAL1; ST3GalA; ST3GalA.1; ST3GalIA; ST3GalIA,1; ST3O
UniProt ID: (Human) Q11201
Entrez Gene ID: (Human) 6482
ganglioside biosynthetic process
N-acetylneuraminate metabolic process
cellular protein modification process
protein phosphorylation
protein N-linked glycosylation
oligosaccharide metabolic process
O-glycan processing
keratan sulfate biosynthetic process
protein N-linked glycosylation via asparagine
sialylation
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