Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: TTEECDMKK MHYVDPDRVK RAQKYAQQVL QKECRPKFAK TSMALLFEHR YSVDLLPFVQ KAPKDSEAES KYDPPFGFRK FSSKVQTLLE LLPEHDLPEH LKAKTCRRCV VIGSGGILHG LELGHTLNQF DVVIRLNSAP VEGYSEHVGN KTTIRMTYPE GAPLSDLEYY SNDLFVAVLF KSVDFNWLQA MVKKETLPFW VRLFFWKQVA EKIPLQPKHF RILNPVIIKE TAFDILQYSE PQSRFWGRDK NVPTIGVIAV VLATHLCDEV SLAGFGYDLN QPRTPLHYFD SQCMAAMNFQ TMHNVTTETK FLLKLVKEGV VKDLSGGIDR EF (88-418 aa encoded by BC065936)
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha 2,3-sialyltransferase V; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; GM3 synthase; GM3-specific sialytransferase; Lactosylceramide alpha-2,3-sialyltransferase; mST3Gal V; Sialyltransferase 9; sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase); sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase); ST3 beta-galactoside alpha-23-sialyltransferase 5; ST3Gal V; ST3GalV
Gene Aliases: 3S-T; [a]2; GM3S; SATI; SIAT9; SIATGM3S; ST3GAL5; ST3GalV; UNQ2510/PRO5998
UniProt ID: (Human) Q9UNP4, (Rat) Q68G12, (Mouse) Q3TMT6
Entrez Gene ID: (Human) 8869, (Rat) 83505, (Mouse) 20454
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