PA5-30289 targets ST3GAL5 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-30289 immunogen is recombinant fragment corresponding to a region within amino acids 174 and 418 of Human ST3GAL5.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: alpha 2,3-sialyltransferase V; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; G; Ganglioside GM3 synthase; GM3 synthase; GM3-specific sialytransferase; Lactosylceramide alpha-2,3-sialyltransferase; mST3Gal V; SATI, SIAT9, SIATGM3S, ST3GalV, CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase, GM3 synthase, ST3Gal V, alpha 2,3-sialyltransferase V, ganglioside GM3 synthase, lactosylceramide alpha-2,3-sialyltransferase, sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Sialyltransferase 9; sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase); sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase); ST3 beta-galactoside alpha-23-sialyltransferase 5; ST3Gal V; ST3GalV
Gene Aliases: 3S-T; [a]2; GM3S; SATI; SIAT9; SIATGM3S; ST3GAL5; ST3GalV; UNQ2510/PRO5998