Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: LDVNFQRKK GDDSDEEDLC ISNKWTFQRT SRRWSRVDDL YTLLPRGDRN GSPGGTGMRN TTSSESVLTD LSEPEVCSIH SESSGGSDSR SQPGQCCTDN PVMLDAPLVS SSLPQPPRDV LNHPFHPKNE KPTRARAKSF LKRMETLRGK GAHGRHKGSG RTGGLVISGP MLQQEPESFK AMQCIQIPNG DLQNSPPPAC RKGLPCSGKS SGESSPSEHS SSGVSTPCLK ERKCHEANKR GGMYLEDLDV LAGTALPDAG DQSRMHEFHS QENLVVHIPK DH (113-393 aa encoded by BC046563)
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 46H23.2; Deleted in liver cancer 2 protein; DLC-2; long intergenic non-protein coding RNA 464; Rho GTPase activating protein on chromosome 13q12; Rho GTPase-activating protein; STA13; StAR-related lipid transfer (START) domain containing 13; StAR-related lipid transfer domain containing 13; StAR-related lipid transfer protein 13; StARD13; START domain-containing protein 13
Gene Aliases: ARHGAP37; DLC2; GT650; LINC00464; STARD13
UniProt ID: (Human) Q9Y3M8
Entrez Gene ID: (Human) 90627
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support