Immunogen sequence: SPERNLWNLK PFTTRDFSIR SLADRLGDLS YLIYVFPDRP KDEVFSKYYT PVLAKAVDGY VKPQIKQVVP EFVNASADAG GSSATYMDQA PSPAVCPQAP YNMYPQNPDH VLDQDGEFDL DETMDVARHV EELLRRPMDS LDSRLSPPAG LFTSARGSLS; Positive Samples: HeLa; Cellular Location: Cytoplasm, Nucleus
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7a2 (cytochrome c oxidase subunit VIIa polypeptide 2), also known as COX7AL or COX7AL1, is an 83 amino acid protein that localizes to the inner mitochondrial membrane and exists as a component of the COX complex, playing an important role in electron transport. COX7a2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein that consists of 114 amino acids and is induced by estrogen.
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Protein Aliases: Signal transducer and activator of transcription 5A
Gene Aliases: MGF; STAT5; STAT5A
UniProt ID: (Human) P42229
Entrez Gene ID: (Human) 6776