Search
Proteintech
STAU1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
14225-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STAU1 Fusion Protein Ag5464 (227-577 aa encoded by BC050432)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GEGEGKSKK ISKKNAAIAV LEELKKLPPL PAVERVKPRI KKKTKPIVKP QTSPEYGQGI NPISRLAQIQ QAKKEKEPEY TLLTERGLPR RREFVMQVKV GNHTAEGTGT NKKVAKRNAA ENMLEILGFK VPQAQPTKPA LKSEEKTPIK KPGDGRKVTF FEPGSGDENG TSNKEDEFRM PYLSHQQLPA GILPMVPEVA QAVGVSQGHH TKDFTRAAPN PAKATVTAMI ARELLYGGTS PTAETILKNN ISSGHVPHGP LTRPSEQLDY LSRVQGFQVE YKDFPKNNKN EFVSLINCSS QPPLISHGIG KDVESCHDMA ALNILKLLSE LDQQSTEMPR TGNGPMSVCG RC (227-577 aa encoded by BC050432)
Target Information
STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 1; protein phosphatase 1, regulatory subunit 150; RNA binding protein; alternatively spliced; RP3-470L14.2; staufen RNA binding protein homolog 1; staufen, RNA binding protein, homolog 1; unnamed protein product
Gene Aliases: 5830401L18Rik; AW549911; C85792; PPP1R150; STAU; STAU1
UniProt ID: (Human) O95793, (Mouse) Q9Z108
Entrez Gene ID: (Human) 6780, (Rat) 84496, (Mouse) 20853
intracellular mRNA localization
positive regulation of viral genome replication
positive regulation by virus of viral protein levels in host cell
lncRNA-mediated post-transcriptional gene silencing
germ cell development
cellular response to oxidative stress
protein localization to synapse
modulation of synaptic transmission
anterograde dendritic transport of messenger ribonucleoprotein complex
modification of postsynaptic structure
positive regulation of long-term synaptic potentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support