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Invitrogen
STAU2 Polyclonal Antibody
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Product Details
PA5-89631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Form
Liquid
Concentration
1.06 mg/mL
Amount
106 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PEYGQGMNPI SRLAQIQQAK KEKEPDYVLL SERGMPRRRE FVMQVKVGNE VATGTGPNKK IAKKNAAEAM LLQLGYKAST NLQDQLEKTG ENKGWSGPKP G; Positive Samples: HeLa, A549, Mouse heart, Rat heart; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus, nucleolus
Target Information
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48. 5% and 59. 9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 2; r-staufen protein; staufen 2; staufen homolog 2; staufen, RNA binding protein, homolog 2; unnamed protein product
Gene Aliases: 39K2; 39K3; STAU2
UniProt ID: (Human) Q9NUL3, (Mouse) Q8CJ67, (Rat) Q68SB1
Entrez Gene ID: (Human) 27067, (Mouse) 29819, (Rat) 171500
germ cell development
intracellular mRNA localization
regulation of actin cytoskeleton organization
cellular response to oxidative stress
protein localization to synapse
eye morphogenesis
regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
anterograde dendritic transport of messenger ribonucleoprotein complex
positive regulation of long term synaptic depression
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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