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Proteintech
STEAP4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
11944-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STEAP4 Fusion Protein Ag2545 (1-283 aa encoded by BC020600)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEKTCIDAL PLTMNSSEKQ ETVCIFGTGD FGRSLGLKML QCGYSVVFGS RNPQKTTLLP SGAEVLSYSE AAKKSGIIII AIHREHYDFL TELTEVLNGK ILVDISNNLK INQYPESNAE YLAHLVPGAH VVKAFNTISA WALQSGALDA SRQAILKKEN PFSTSSAWLS DSYVALGILG FFLFVLLGIT SLPSVSNAVN WREFRFVQSK LGYLTLILCT AHTLVYGGKR FLSPSNLRWY LPAAYVLGLI IPCTVLVIKF VLIMPCVDNT LTRIRQGWER NSKH (1-283 aa encoded by BC020600)
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ab1-219; DKFZp666D049; dudulin 4; FLJ23153; liver regeneration-related protein LRRG044; seven chromosome locus associated with HCC; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; sixTransMembrane protein of prostate 2; STEAP family member 4; STMP2v1; STMP2v2; Tnfa-induced adipose-related protein; tumor necrosis factor, alpha-induced protein 9; tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein; unnamed protein product
Gene Aliases: 1110021O17Rik; SchLAH; STAMP2; TIARP; TNFAIP9
UniProt ID: (Human) Q687X5, (Mouse) Q923B6, (Rat) Q4V8K1
Entrez Gene ID: (Human) 79689, (Mouse) 117167, (Rat) 499991
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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