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          • Primary Antibodies ›
          • STEAP4 Antibodies

          Proteintech

          STEAP4 Polyclonal Antibody

          44 References
          View all (7) STEAP4 antibodies

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          Cite STEAP4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          STEAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          STEAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          STEAP4 Antibody (11944-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using 11944-1-AP (STEAP4 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          STEAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          STEAP4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          STEAP4 Antibody in Western Blot (WB)
          STEAP4 Antibody in Western Blot (WB)
          STEAP4 Antibody in Western Blot (WB)
          STEAP4 Antibody in Western Blot (WB)
          STEAP4 Antibody in Western Blot (WB)
          STEAP4 Antibody in Immunoprecipitation (IP)
          STEAP4 Polyclonal Antibody

          Product Details

          11944-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 25 publications 25 publications

          Immunohistochemistry (IHC)

          -
          View 15 publications 15 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          STEAP4 Fusion Protein Ag2545 (1-283 aa encoded by BC020600)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Amount

          19.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MEKTCIDAL PLTMNSSEKQ ETVCIFGTGD FGRSLGLKML QCGYSVVFGS RNPQKTTLLP SGAEVLSYSE AAKKSGIIII AIHREHYDFL TELTEVLNGK ILVDISNNLK INQYPESNAE YLAHLVPGAH VVKAFNTISA WALQSGALDA SRQAILKKEN PFSTSSAWLS DSYVALGILG FFLFVLLGIT SLPSVSNAVN WREFRFVQSK LGYLTLILCT AHTLVYGGKR FLSPSNLRWY LPAAYVLGLI IPCTVLVIKF VLIMPCVDNT LTRIRQGWER NSKH (1-283 aa encoded by BC020600)

          Target Information

          The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Ab1-219; DKFZp666D049; dudulin 4; Dudulin-4; FLJ23153; Metalloreductase STEAP4; seven chromosome locus associated with HCC; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STEAP family member 4; STMP2v1; STMP2v2; Tnfa-induced adipose-related protein; Tumor necrosis factor, alpha-induced protein 9; Tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein; unnamed protein product

          View more View less

          Gene Aliases: 1110021O17Rik; AI481214; SchLAH; STAMP2; STEAP4; TIARP; TNFAIP9

          View more View less

          UniProt ID: (Human) Q687X5, (Rat) Q4V8K1, (Mouse) Q923B6

          View more View less

          Entrez Gene ID: (Human) 79689, (Rat) 499991, (Mouse) 117167

          View more View less

          Function(s)
          cupric reductase activity electron carrier activity oxidoreductase activity heme binding metal ion binding ferric-chelate reductase (NADPH) activity FAD binding
          Process(es)
          copper ion import fat cell differentiation iron ion homeostasis oxidation-reduction process ferric iron import into cell transport ion transport iron ion transport iron assimilation protein homotrimerization
          It has to be done as per old AB suggested Products section.

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