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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 34 and 333 of Human STK36|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28897 targets STK36 in WB applications and shows reactivity with Human and mouse samples.
The PA5-28897 immunogen is recombinant fragment corresponding to a region within amino acids 34 and 333 of Human STK36.
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FU; Fused homolog; serine/threonine kinase 36 (fused homolog, Drosophila); Serine/threonine-protein kinase 36; STK36; testicular tissue protein Li 188
1700112N14Rik; B930045J24; FU; Fused; KIAA1278; mKIAA1278; STK36