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Invitrogen
STK36 Polyclonal Antibody
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Product Details
PA5-28897
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human STK36. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D, IMR32, Jurkat, HeLa, mouse brain.
Predicted reactivity: Mouse (97%), Rat (96%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fused homolog; serine/threonine kinase 36 (fused homolog, Drosophila); Serine/threonine-protein kinase 36; STK36; testicular tissue protein Li 188
Gene Aliases: 1700112N14Rik; B930045J24; FU; Fused; KIAA1278; mKIAA1278; STK36
UniProt ID: (Human) Q9H9N9, (Mouse) Q69ZM6
Entrez Gene ID: (Human) 27148, (Mouse) 269209
magnesium ion binding
protein serine/threonine kinase activity
protein binding
ATP binding
transcription factor binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
epithelial cilium movement
protein phosphorylation
positive regulation of hh target transcription factor activity
brain development
post-embryonic development
cilium assembly
positive regulation of smoothened signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
multicellular organism development
phosphorylation
cell projection organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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