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Product Details
PA5-55625
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human STK36. Recombinant protein control fragment (Product #RP-95073).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648022
Product Specific Information
Immunogen sequence: EMWTVLWHRF SMVLRLPEEA SAQEGELSLS SPPSPEPDWT LISPQGMAAL LSLAMATFTQ EPQLCLSCLS QHGSILMSIL KH^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.
Target Information
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fused homolog; Serine/threonine-protein kinase 36; STK36; testicular tissue protein Li 188
Gene Aliases: FU; KIAA1278; STK36
UniProt ID: (Human) Q9H9N9
Entrez Gene ID: (Human) 27148
epithelial cilium movement
protein phosphorylation
positive regulation of hh target transcription factor activity
brain development
post-embryonic development
cilium assembly
positive regulation of smoothened signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
Performance Guarantee
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