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STMN3 Polyclonal Antibody

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STMN3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human colon cancer using 11311-1-AP (STMN3 antibody) at dilution of 1:50 (under 10x lens).

STMN3 Antibody in Western Blot (WB) — Human brain tissue were subjected to SDS PAGE followed by western blot with 11311-1-AP (STMN3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

STMN3 Antibody in Immunoprecipitation (IP) — IP result of anti-STMN3 (IP:11311-1-AP, 3ug; Detection:11311-1-AP 1:2000) with mouse brain tissue lysate 8000ug.

Product Details

11311-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:4,000	View 2 publications 2 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunoprecipitation (IP)	0.5-4.0 µg	-
Immunohistochemistry (IHC)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	STMN3 Fusion Protein Ag1853 (1-180 aa encoded by BC009381) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.45 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MASTISAYK EKMKELSVLS LICSCFYTQP HPNTVYQYGD MEVKQLDKRA SGQSFEVILK SPSDLSPESP MLSSPPKKKD TSLEELQKRL EAAEERRKTQ EAQVLKQLAE RREHEREVLH KALEENNNFS RQAEEKLNYK MELSKEIREA HLAALRERLR EKELHAAEVR RNKEQREEMS G (1-180 aa encoded by BC009381)

Target Information

This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP.

Molecular cancer therapeutics

Xie X,Bartholomeusz C,Ahmed AA,Kazansky A,Diao L,Baggerly KA,Hortobagyi GN,Ueno NT

Sat Jun 01 00:00:00 EDT 2013

Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer.

Cancer research

Singer S,Malz M,Herpel E,Warth A,Bissinger M,Keith M,Muley T,Meister M,Hoffmann H,Penzel R,Gdynia G,Ehemann V,Schnabel PA,Kuner R,Huber P,Schirmacher P,Breuhahn K

Sun Mar 15 00:00:00 EDT 2009

Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer.

Cancer research

Singer S,Malz M,Herpel E,Warth A,Bissinger M,Keith M,Muley T,Meister M,Hoffmann H,Penzel R,Gdynia G,Ehemann V,Schnabel PA,Kuner R,Huber P,Schirmacher P,Breuhahn K

Sun Mar 15 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: Hippocampus abundant transcript 3; SCG10-like protein; SCG10-like-protein; SCG10-related protein HiAT3; Scgn10 like-protein; Stathmin-3; stathmin-like 3

Gene Aliases: 9330161A03Rik; AI604839; R75323; SCLIP; STMN3

UniProt ID: (Human) Q9NZ72, (Mouse) O70166, (Rat) Q9JHU6

Entrez Gene ID: (Human) 50861, (Mouse) 20262, (Rat) 29246

Function(s)

microtubule depolymerization nervous system development regulation of microtubule polymerization or depolymerization cytoplasmic microtubule organization neuron projection development negative regulation of Rac protein signal transduction regulation of GTPase activity regulation of cytoskeleton organization

Process(es)

tubulin binding protein domain specific binding protein binding protein C-terminus binding

STMN3 Polyclonal Antibody

Product Details

11311-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Immunohistochemistry (IHC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

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