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Proteintech
STOML1 Polyclonal Antibody
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Product Details
12862-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STOML1 Fusion Protein Ag3978 (79-398 aa encoded by BC034379)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LKIVPTYER MIVFRLGRIR TPQGPGMVLL LPFIDSFQRV DLRTRAFNVP PCKLASKDGA VLSVGADVQF RIWDPVLSVM TVKDLNTATR MTAQNAMTKA LLKRPLREIQ MEKLKISDQL LLEINDVTRA WGLEVDRVEL AVEAVLQPPQ DSPAGPNLDS TLQQLALHFL GGSMNSMAGG APSPGPADTV EMVSEVEPPA PQVGARSSPK QPLAEGLLTA LQPFLSEALV SQVGACYQFN VVLPSGTQSA YFLDLTTGRG RVGHGVPDGI PDVVVEMAEA DLRALLCREL RPLGAYMSGR LKVKGDLAMA MKLEAVLRAL K (79-398 aa encoded by BC034379)
Target Information
Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EPB72-like 1; EPB72-like protein 1; Protein unc-24 homolog; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin-like 1; Stomatin-like protein 1; Stomatin-related protein; STORP
Gene Aliases: 1810015E19Rik; AI847431; hUNC-24; MSTP019; RGD1559463; SLP-1; SLP1; STOML1; STORP; UNC24; WPB72
UniProt ID: (Human) Q9UBI4, (Mouse) Q8CI66
Entrez Gene ID: (Human) 9399, (Rat) 300748, (Mouse) 69106
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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