|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 14 amino acid synthetic peptide near the carboxy terminus of human STOX1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 ug/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is human liver tissue lysate.
PA5-34398 can be used with blocking peptide PEP-1440.
STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.