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Product Details
PA5-65193
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human STOX1. Recombinant protein control fragment (Product #RP-105938).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663792
Product Specific Information
Immunogen sequence: DESRLMPASMT YLVSMESCAE SAQENAAPIS HCQSCQCFRD MHTQDVQEAP VAAEVTRKSH RGLGESVSWV QNGAVSVSAE HH
Highest antigen sequence identity to the following orthologs - mouse 47%, rat 43%.
Target Information
STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PEE4; Storkhead-box protein 1; Winged-helix domain-containing protein
Gene Aliases: C10orf24; STOX1
UniProt ID: (Human) Q6ZVD7
Entrez Gene ID: (Human) 219736
transcription, DNA-templated
mitotic nuclear division
positive regulation of cell proliferation
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
positive regulation of peptidyl-threonine phosphorylation
regulation of mitochondrion organization
positive regulation of G2/M transition of mitotic cell cycle
positive regulation of peptidyl-serine phosphorylation
inner ear development
positive regulation of epithelial cell proliferation
cell division
regulation of mitochondrial membrane potential
positive regulation of protein kinase B signaling
regulation of transcription from RNA polymerase II promoter in response to hypoxia
cellular response to nitrosative stress
regulation of mitochondrial DNA metabolic process
regulation of response to oxidative stress
positive regulation of cyclin-dependent protein kinase activity
positive regulation of otic vesicle morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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