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Invitrogen
STS Polyclonal Antibody
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FIGURE: 1 / 2
STS Antibody (PA5-115973) in ICC/IF
Immunocytochemistry analysis of STS in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115973). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115973
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human STS(Accession P08842), corresponding to amino acid residues V486-R536.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Steroid sulfatase.
Target Information
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arylsulfatase C; ASC; Estrone sulfatase; Steroid sulfatase; Steryl-sulfatase; Steryl-sulfate sulfohydrolase
Gene Aliases: ARSC; ARSC1; ASC; ES; SSDD; STS; XLI
UniProt ID: (Human) P08842
Entrez Gene ID: (Human) 412
glycosphingolipid metabolic process
steroid catabolic process
female pregnancy
learning or memory
positive regulation of cell proliferation
epidermis development
response to pH
response to organic cyclic compound
response to peptide hormone
skin development
response to estrogen
post-translational protein modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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