Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
1:100-1:1,000 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
1:100-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human STX17. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.85 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.025% ProClin 300 |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2608436 |
Recommended positive controls: 293T, A431, HeLa, and HepG2 cells.
Predicted reactivity: Mouse (89%), Rat (86%), Rhesus Monkey (99%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Syntaxin-17
Gene Aliases: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351; STX17
UniProt ID: (Human) P56962, (Rat) Q9Z158, (Mouse) Q9D0I4
Entrez Gene ID: (Human) 55014, (Rat) 252853, (Mouse) 67727
Molecular Function:
SNARE protein
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