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Product Details
PA5-51797
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:500-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
0.25-2 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human STX18 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2648056 |
Product Specific Information
Immunogen sequence: VKRVVDKKRL SKLEPEPNTK TRESTSSEKV SQSPSKDSEE NPATEERPEK ILAETQPELG TWGDGKGEDE LSPEEIQMFE QENQRLIGEM NSLFDEVRQI EGRVVEISRL QEIFTEKVLQ QEAEIDSIHQ LVVGATENIK EGNEDIREAI
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.
Target Information
Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Syntaxin 18 mainly localizes to the endoplasmic reticulum (ER), and functions in transport between the ER and Golgi. Syntaxin 18 also plays a role in ER-mediated phagocytosis, possibly by regulating the specific fusion of the ER and plasma or phagosomal membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 9 protein; Syntaxin-18
Gene Aliases: GIG9; STX18; Ufe1
UniProt ID: (Human) Q9P2W9
Entrez Gene ID: (Human) 53407
Molecular Function:
SNARE protein
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