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STXB1 Polyclonal Antibody
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FIGURE: 1 / 5
STXB1 Antibody (OSS00302W-100UL) in IHC (P)
IHC-P on paraffin sections of rat cerebellum. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 mL 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructi... View More
Product Details
OSS00302W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from n-terminal region of mouse Syntaxin binding protein 1 (STXB1, Unc-18A) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Syntaxin-binding protein 1.
Target Information
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rbSec1; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1; unnamed protein product
Gene Aliases: AI317162; AI326233; ANC18HA; DEE4; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-Sec1; NSEC1; NSEC1A; P67; Rb-sec1; RBSEC1; rbSec1A; rbSec1B; Sec1; STXBP1; Sxtbp1; unc-18A; UNC18; Unc18-1; UNC18A; Unc18h
UniProt ID: (Human) P61764, (Mouse) O08599, (Rat) P61765
Entrez Gene ID: (Human) 6812, (Mouse) 20910, (Rat) 25558
platelet degranulation
developmental process involved in reproduction
intracellular protein transport
exocytosis
vesicle docking involved in exocytosis
neurotransmitter secretion
neuromuscular synaptic transmission
axon target recognition
regulation of synaptic vesicle priming
protein transport
synaptic vesicle priming
synaptic vesicle maturation
vesicle-mediated transport
negative regulation of protein complex assembly
regulation of vesicle fusion
regulation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic transmission, GABAergic
response to estradiol
SNARE complex assembly
regulation of SNARE complex assembly
positive regulation of mast cell degranulation
negative regulation of neuron apoptotic process
regulated exocytosis
positive regulation of exocytosis
positive regulation of calcium ion-dependent exocytosis
protein stabilization
neuron apoptotic process
establishment of localization in cell
long term synaptic depression
platelet aggregation
cellular response to interferon-gamma
protein localization to plasma membrane
presynaptic dense core vesicle exocytosis
positive regulation of vesicle docking
positive regulation of glutamate secretion, neurotransmission
regulation of regulated secretory pathway
regulation of acrosomal vesicle exocytosis
transport
synaptic vesicle fusion to presynaptic active zone membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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