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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Syntaxin-binding protein 5.
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ30922; L Nbla04300; Lethal(2) giant larvae protein homolog 3; MGC141942; MGC141968; RP11-361F15.4; STXB5; Syntaxin-binding protein 5; tomosyn; tomosyn 1; Tomosyn-1
Gene Aliases: 0710001E20Rik; 4930565N16Rik; AW742610; LGL3; Llgl3; mKIAA1006; Stxbp5
UniProt ID: (Rat) Q9WU70
Entrez Gene ID: (Rat) 81022, (Mouse) 78808
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