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Proteintech
STXBP4 Polyclonal Antibody
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Product Details
14231-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STXBP4 Fusion Protein Ag5471 (1-245 aa encoded by BC041485)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
39 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MIGVSFEEA KSIITGAKLS TRLESAWEIA FIRQKSDNIQ PENLSCTSLI EASGEYGPQA STLSLFSSPP EILIPKTSST PKTNNDILSS CEIKTGYNKT VQIPITSENS TVGLSNTDVA SAWTENYGLQ EKISLNPSVR FKAEKLEMAL NYLGIQPTKE QHQALRQQVQ ADSKGTVSFG DFVQVARNLF CLQLDEVNVG AHEISNILDS QLLPCDSSEA DEMERLKCER DDALKEVNTL KWPGQN (1-245 aa encoded by B C041485)
Target Information
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ16496; MGC149829; MGC50337; STX4-interacting protein; syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin-binding protein 4; unnamed protein product
Gene Aliases: 6030470M02Rik; STXBP4; Synip
UniProt ID: (Human) Q6ZWJ1, (Mouse) Q9WV89
Entrez Gene ID: (Human) 252983, (Mouse) 20913, (Rat) 303443
protein targeting
response to stress
cellular response to DNA damage stimulus
insulin receptor signaling pathway
regulation of glucose transport
positive regulation of keratinocyte proliferation
protein stabilization
regulation of transport
regulation of insulin secretion involved in cellular response to glucose stimulus
cellular response to interferon-gamma
positive regulation of cell cycle G1/S phase transition
glucose transport
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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