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Product Details
24512-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STXBP5 Fusion Protein Ag21629 (515-610 aa encoded by BC113382)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MLCIAGVSA HVIIYRFSKQ EVITEVIPML EVRLLYEIND VETPEGEQPP PLPTPVGGSN PQPIPPQSHP STSSSSSDGL RDNVPCLKVK NSPLKQS (515-610 aa encoded by BC113382 )
Target Information
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ30922; L Nbla04300; Lethal(2) giant larvae protein homolog 3; MGC141942; MGC141968; putative protein product of Nbla04300; RP11-361F15.4; STXB5; syntaxin binding protein 5 (tomosyn); Syntaxin-binding protein 5; tomosyn; Tomosyn-1
Gene Aliases: LGL3; LLGL3; Nbla04300; STXBP5
UniProt ID: (Human) Q5T5C0, (Rat) Q9WU70
Entrez Gene ID: (Human) 134957, (Rat) 81022
Molecular Function:
membrane trafficking regulatory protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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