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Proteintech
SUCLA2 Polyclonal Antibody
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Product Details
12627-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SUCLA2 Fusion Protein Ag3319 (24-353 aa encoded by BC027587)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AQRAAAQVL GSSGLFNNHG LQVQQQQQRN LSLHEYMSME LLQEAGVSVP KGYVAKSPDE AYAIAKKLGS KDVVIKAQVL AGGRGKGTFE SGLKGGVKIV FSPEEAKAVS SQMIGKKLFT KQTGEKGRIC NQVLVCERKY PRREYYFAIT MERSFQGPVL IGSSHGGVNI EDVAAESPEA IIKEPIDIEE GIKKEQALQL AQKMGFPPNI VESAAENMVK LYSLFLKYDA TMIEINPMVE DSDGAVLCMD AKINFDSNSA YRQKKIFDLQ DWTQEDERDK DAAKANLNYI GLDGNIGCLV NGAGLAMATM DIIKLHGGTP ANFLDVGGGA T (24-353 aa encoded by BC027587)
Target Information
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; ATP-specific succinyl-CoA synthetase, beta subunit; beta-SCoAS; Itaconyl--CoA ligase [ADP-forming] subunit beta; long intergenic non-protein coding RNA 444; Malyl--CoA ligase [ADP-forming] subunit beta; mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta; renal carcinoma antigen NY-REN-39; RP11-528D24.2; SCS-betaA; SCSbetaA; Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; succinate-CoA ligase ADP-forming beta subunit; succinate-CoA ligase beta subunit; succinate-Coenzyme A ligase, ADP-forming, beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase beta-A chain; unnamed protein product
Gene Aliases: 4930547K18Rik; A-BETA; A-SCS; LINC00444; MTDPS5; SCS-betaA; SUCLA2
UniProt ID: (Human) Q9P2R7, (Mouse) Q9Z2I9
Entrez Gene ID: (Human) 8803, (Rat) 361071, (Mouse) 20916
nucleotide binding
magnesium ion binding
catalytic activity
succinate-CoA ligase (ADP-forming) activity
protein binding
ATP binding
ligase activity
metal ion binding
acyl-CoA ligase activity
succinate-CoA ligase activity
3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity
fatty acid ligase activity
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
benzoyl acetate-CoA ligase activity
2,4-dichlorobenzoate-CoA ligase activity
pivalate-CoA ligase activity
cyclopropanecarboxylate-CoA ligase activity
adipate-CoA ligase activity
citronellyl-CoA ligase activity
mentha-1,3-dione-CoA ligase activity
thiophene-2-carboxylate-CoA ligase activity
2,4,4-trimethylpentanoate-CoA ligase activity
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
branched-chain acyl-CoA synthetase (ADP-forming) activity
aryl-CoA synthetase (ADP-forming) activity
3-hydroxypropionyl-CoA synthetase activity
perillic acid:CoA ligase (ADP-forming) activity
perillic acid:CoA ligase (AMP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
pristanate-CoA ligase activity
malonyl-CoA synthetase activity
ligase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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