This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
PA5-29952 targets Suppressor of Fused in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29952 immunogen is recombinant fragment corresponding to a region within amino acids 267 and 484 of Human Suppressor of Human Fused.
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SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).
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Protein Aliases: PRO1280; SUFUH; SUFUXL; Suppressor of fused homolog
Gene Aliases: PRO1280; Su(fu); SUFU; SUFUH; SUFUXL; UNQ650/PRO1280