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Proteintech
SULF2 Polyclonal Antibody
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Product Details
12260-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SULF2 Fusion Protein Ag2915 (722-870 aa encoded by BC020962)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
39 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPGLTCFTH DNQHWQTAPF WTLGPFCACT SANNNTYWCM RTINETHNFL FCEFATGFLE YFDLNTDPYQ LMNAVNTLDR DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW PEMKRPSSKS LGQLWEGWEG (722-870 aa encoded by BC020962)
Target Information
Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Arylsulfatase; DKFZp313E091; Extracellular sulfatase Sulf-2; FLJ44488; FLJ90554; hSulf-2; MGC126411; mSulf-2; N-acetylglucosamine-6-sulfatase; OTTHUMP00000031223; RP5-1049G16.1; sulfatase FP2
Gene Aliases: 2010004N24Rik; AU020235; HSULF-2; KIAA1247; mKIAA1247; MSulf-2; SULF2; UNQ559/PRO1120
UniProt ID: (Human) Q8IWU5, (Mouse) Q8CFG0
Entrez Gene ID: (Human) 55959, (Rat) 311642, (Mouse) 72043
arylsulfatase activity
calcium ion binding
protein binding
glycosaminoglycan binding
N-acetylglucosamine-6-sulfatase activity
sulfuric ester hydrolase activity
hydrolase activity
metal ion binding
catalytic activity
alkyl sulfatase activity
endosulfan hemisulfate sulfatase activity
endosulfan sulfate hydrolase activity
hydrolase
kidney development
chondrocyte development
glomerular filtration
response to wounding
positive regulation of vascular endothelial growth factor production
esophagus smooth muscle contraction
positive regulation of Wnt signaling pathway
heparan sulfate proteoglycan metabolic process
glomerular basement membrane development
glial cell-derived neurotrophic factor receptor signaling pathway
negative regulation of fibroblast growth factor receptor signaling pathway
embryonic skeletal system development
cartilage development
bone development
innervation
positive regulation of canonical Wnt signaling pathway
liver regeneration
positive regulation of endothelin production
regulation of hepatocyte proliferation
sulfur compound metabolic process
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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