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Invitrogen
SULT1A1 Polyclonal Antibody
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Product Details
PA5-102435
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SULT1A1(Accession P50225), corresponding to amino acid residues G65-P115.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SULT1A1.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; Aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; Phenol-sulfating phenol sulfotransferase 1; phenol/aryl sulfotransferase; PST-1; ST1A1; ST1A3; ST1A4; Sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; Ts-PST; Tyrosine-ester sulfotransferase
Gene Aliases: AI266890; ASTIV; HAST1/HAST2; Mx-ST; OK/SW-cl.88; P-PST; P-PST 1; PST; PST-1; ST1A1; ST1A3; Stm; STP; STP1; SULT1A1; Sult1a3; ts-PST; TSPST1
UniProt ID: (Human) P50225, (Rat) P17988
Entrez Gene ID: (Human) 6817, (Mouse) 20887, (Rat) 83783
aryl sulfotransferase activity
protein binding
sulfotransferase activity
transferase activity
flavonol 3-sulfotransferase activity
steroid sulfotransferase activity
3'-phosphoadenosine 5'-phosphosulfate binding
nucleotide binding
N-acetylglucosamine 6-O-sulfotransferase activity
N-acetylgalactosamine 4-O-sulfotransferase activity
heparan sulfate 2-O-sulfotransferase activity
HNK-1 sulfotransferase activity
tyrosine-ester sulfotransferase activity
heparan sulfate 6-O-sulfotransferase activity
trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
1-phenanthrol sulfotransferase activity
3-phenanthrol sulfotransferase activity
4-phenanthrol sulfotransferase activity
trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
9-phenanthrol sulfotransferase activity
2-phenanthrol sulfotransferase activity
phenanthrol sulfotransferase activity
1-hydroxypyrene sulfotransferase activity
protein homodimerization activity
galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
cholesterol sulfotransferase activity
hydroxyjasmonate sulfotransferase activity
transferase
ethanol catabolic process
catecholamine metabolic process
lipid metabolic process
xenobiotic metabolic process
steroid metabolic process
estrogen metabolic process
amine metabolic process
flavonoid metabolic process
thyroid hormone metabolic process
dopamine catabolic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
sulfation
drug metabolic process
4-nitrophenol metabolic process
response to glucocorticoid
regulation of blood pressure
response to activity
response to insecticide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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