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Invitrogen
SULT2A1 Polyclonal Antibody
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FIGURE: 1 / 6
SULT2A1 Antibody (PA5-89604) in IHC (P)
Immunohistochemistry analysis of SULT2A1 in paraffin-embedded human gastric cancer. Samples were incubated with SULT2A1 Polyclonal antibody (Product # PA5-89604) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-89604
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
26 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse skeletal muscle; Cellular Location: Cytoplasm
Target Information
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alcohol sulfotransferase; alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotransferase; Bile salt sulfotransferase 1; bile-salt sulfotranasferase 2A1; bile-salt sulfotransferase 2A1; Dehydroepiandrosterone sulfotransferase; DHEA-ST; HST; Hydroxysteroid Sulfotransferase; hydroxysteroid sulfotransferase a; ST; ST-20; ST2; ST2A1; Sulfotransferase 2A1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; sulfotransferase hydroxysteroid gene 2; sulfotransferase, DHEA preferring; sulfotransferase, hydroxysteroid preferring 1; sulfotransferase, hydroxysteroid preferring 2; SULT2A3; unnamed protein product
Gene Aliases: DHEA-ST; DHEA-ST8; DHEAS; HST; hSTa; mSTa1; Smp-2; ST2; ST2A1; ST2A3; STa; Sta1; STD; Sth1; Sth2; SULT2A1; SULT2A3
UniProt ID: (Human) Q06520, (Mouse) P52843, (Rat) P15709
Entrez Gene ID: (Human) 6822, (Mouse) 20859, (Rat) 24912
ethanol catabolic process
lipid metabolic process
xenobiotic metabolic process
steroid metabolic process
cholesterol metabolic process
lipid catabolic process
bile acid catabolic process
thyroid hormone metabolic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
sulfation
aging
metabolic process
response to activity
response to insecticide
drug metabolic process
response to nutrient levels
cellular response to vitamin D
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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