Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. SULT4A1 isoforms a and b are selectively expressed in brain tissue. Isoform a is the predominant of the two isoforms of this protein. Isoform b includes an alternate segment, compared to isoform a, that causes a frameshift. The resulting protein (isoform b) has a distinct and shorter C-terminus when compared to isoform a.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Brain sulfotransferase-like protein; hBR-STL; mBR-STL; nervous system cytosolic sulfotransferase; Nervous system sulfotransferase; NST; rBR-STL; ST4A1; Sulfotransferase 4A1; sulfotransferase family 4A, member 1; sulfotransferase-related protein
Gene Aliases: 2400007A17Rik; AI853543; BR-STL-1; BRSTL1; DJ388M5.3; hBR-STL-1; NST; ST4A1; SULT4A1; SULTX3
Molecular Function: transferase