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Invitrogen
SUMO2/SUMO3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-20959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide near the carboxy terminus of human SUMO2.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is rat liver tissue lysate.
PA5-20959 can be used with blocking peptide PEP-1073.
Target Information
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GMP1; Sentrin; sentrin 2; sentrin-2; SMT3 homolog 2; SMT3 homolog 3; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 3; SMT3 supressor of mif two 3 homolog 2; SMT3C; SMT3H1; SMT3H3; SUMO-1; SUMO-2; SUMO-3; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B; UBL1; unnamed protein product
Gene Aliases: 2810014B19Rik; D10Ertd345e; HSMT3; SMT3A; SMT3B; SMT3H1; SMT3H2; SUMO-2; SUMO-3
UniProt ID: (Human) P61956, (Human) P55854, (Rat) P61959, (Mouse) P61957, (Mouse) Q9Z172, (Rat) Q5XIF4
Entrez Gene ID: (Human) 6613, (Human) 6612, (Rat) 690244, (Mouse) 170930, (Mouse) 20610, (Rat) 499417
protein sumoylation
regulation of protein localization to nucleus
protein localization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein sumoylation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein localization to nucleus
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
translation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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