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SUPT16H Polyclonal Antibody
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Product Details
BS-7879R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SUPT16H/CDC68, amino acids 601-700.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT, interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chromatin-specific transcription elongation factor 140 kDa subunit; facilitates chromatin remodeling 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT; FACT 140 kDa subunit; FACT complex subunit SPT16; FACTp140; FLJ10857; FLJ14010; FLJ34357; HGNC:11465; hSPT16; suppressor of Ty 16 homolog; TFIIE-interacting factor
Gene Aliases: CDC68; FACT140; FACTP140; NEDDFAC; SPT16; SPT16/CDC68; Supt16; SUPT16H
UniProt ID: (Human) Q9Y5B9, (Mouse) Q920B9
Entrez Gene ID: (Human) 11198, (Mouse) 114741, (Rat) 305851
DNA replication
DNA repair
nucleosome assembly
nucleosome disassembly
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
cellular response to DNA damage stimulus
positive regulation of DNA-templated transcription, elongation
transcription, DNA-templated
regulation of transcription, DNA-templated
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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