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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MEMVQKLQK VGSLEPRVEV LINRINEVQQ AKKKANKDLG EARTICEALQ KELDSLHGEK VHLKEILSKK QETLRILRLH CQEKESEAHR KHTMLQDCKE RISALNLQIE EEKNKQRQLR LAFEEQLEDL MGQHKDLWDF HMPERLAREI CALDSSKEQL LKEEKLVKAT LEDVKHQLCS LCGAEGPSTL DEGLFLRSQE AAATVQLFQE EHRKAEELLA AAAQRHQQLQ QKCQQQQQKR QRLKEELEKH GMQVPAQAQS TQEEEAGPGD VASPKPLKGE RPGAARQAGP DVLIGQEDTL HPDLSPRGFQ EIKELF (1-315 aa encoded by B C034821)
SYCE1 (synaptonemal complex central element protein 1), also known as CT76 (cancer/testis antigen 76), is a 351 amino acid nuclear protein that belongs to the SYCE family and exists as three alternatively spliced isoforms. Colocalizing with SYCE2 on chromatin, SYCE1 exists as a homodimer and is found in the transverse central elements of the central region between lateral elements of the synaptonemal complexes (SCS). The transverse central element of the SCS is formed between homologous chromosomes during meiotic prophase and requires SYCP1.
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Protein Aliases: cancer/testis antigen 76; epididymis secretory sperm binding protein; telomeric protein; unnamed protein product
Gene Aliases: 4933406J07Rik; C10orf94; CT76; POF12; SPGF15
UniProt ID: (Human) Q8N0S2, (Rat) Q5XHZ2, (Mouse) Q9D495
Entrez Gene ID: (Human) 93426, (Rat) 502372, (Mouse) 74075
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