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Immunogen sequence: MAESRQDLE EEYEPQFLRL LERKEAGTKA LQRTQAEIQE MKEALRPLQA EARQLRLQNR NLEDQIALVR QKRDEEVQQY REQLEEMEER QRQLRNGVQL QQQKNKEMEQ LRLSLAEELS TYKAMLLPKS LEQADAPTSQ AGGMETQSQG AV (332-482 aa encoded by BC119700)
This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: intermediate filament protein syncoilin; synci; Syncoilin; Syncoilin intermediate filament 1; syncoilin, intermediate filament 1; Syncoilin-1
Gene Aliases: 1110057H03Rik; SNIP4; SYNC; SYNC1; SYNCOILIN
UniProt ID: (Human) Q9H7C4, (Mouse) Q9EPM5
Entrez Gene ID: (Human) 81493, (Mouse) 68828
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