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Proteintech
SYNJ2 Polyclonal Antibody
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Product Details
30391-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RRKKSAPAAF HLQVLQSNSQ LLQGLTYNSS DSPSGHPPAA GTVFPQGDFL STSSATSPDS DGTKAMKPEA APLLGDYQDP FWNLLHHPKL LNNTWLSKSS DPLDSGTRSP KRDPIDPVSA GASAAKAELP PDHGHKTLGH WVTISDQEKR TALQVFDPLA KT
Target Information
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inositol phosphate 5'-phosphatase 2; inositol polyphosphate 5'-phosphatase; inositol polyphosphate-5-phosphatase H; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2; Synaptojanin-2; unnamed protein product
Gene Aliases: AI481647; INPP5H; KIAA0348; mKIAA0348; SJ2; SYNJ2
UniProt ID: (Human) O15056, (Mouse) Q9D2G5
Entrez Gene ID: (Human) 8871, (Mouse) 20975
nucleic acid binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
protein binding
hydrolase activity
phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
phosphatidylinositol phosphate phosphatase activity
nucleotide binding
inositol-polyphosphate 5-phosphatase activity
SH3 domain binding
PDZ domain binding
phosphoric ester hydrolase activity
phosphatidylinositol monophosphate phosphatase activity
phosphatase
lipid metabolic process
phosphatidylinositol biosynthetic process
phosphatidylinositol-3-phosphate biosynthetic process
phosphatidylinositol dephosphorylation
synaptic vesicle endocytosis
membrane organization
dephosphorylation
inositol phosphate dephosphorylation
intracellular distribution of mitochondria
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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