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Invitrogen
SYNM Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-60647
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:1,000-1:2,500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human SYNM |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2648145 |
Product Specific Information
Immunogen sequence: MDVSNVEAIR SRTQEAGALG VSDRGSWRDA DSRNDQAVGV SFKASAGEGD QAHREQGKEQ AMFDKKVQLQ RMVDQRSVIS D
Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.
Target Information
Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Desmuslin; Synemin; synemin alpha; synemin beta; synemin, intermediate filament protein
Gene Aliases: DMN; KIAA0353; SYN; SYNM
UniProt ID: (Human) O15061
Entrez Gene ID: (Human) 23336
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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