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Proteintech
SYTL2 Polyclonal Antibody
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Product Details
12359-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYTL2 Fusion Protein Ag3023 (7-382 aa encoded by BC015540)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSKSVPAFL QDESDDRETD TASESSYQLS RHKKSPSSLT NLSSSSGMTS LSSVSGSVMS VYSGDFGNLE VKGNIQFAIE YVESLKELHV FVAQCKDLAA ADVKKQRSDP YVKAYLLPDK GKMGKKKTLV VKKTLNPVYN EILRYKIEKQ ILKTQKLNLS IWHRDTFKRN SFLGEVELDL ETWDWDNKQN KQLRWYPLKR KTAPVALEAE NRGEMKLALQ YVPEPVPGKK LPTTGEVHIW VKECLDLPLL RGSHLNSFVK CTILPDTSRK SRQKTRAVGK TTNPIFNHTM VYDGFRPEDL MEACVELTVW DHYKLTNQFL GGLRIGFGTG KSYGTEVDWM DSTSEEVALW EKMVNSPNTW IEATLPLRML LIAKISK (7-382 aa encoded by BC015540)
Target Information
SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Breast cancer-associated antigen SGA-72M; chromosome 11 synaptotagmin; Exophilin-4; protein phosphatase 1, regulatory subunit 151; synaptotagmin-like 2; Synaptotagmin-like protein 2
Gene Aliases: AI266830; CHR11SYT; EXO4; KIAA1597; mKIAA1597; PPP1R151; SGA72M; SLP2; SLP2A; SYTL2
UniProt ID: (Human) Q9HCH5, (Mouse) Q99N50
Entrez Gene ID: (Human) 54843, (Rat) 361604, (Mouse) 83671
exocytosis
intracellular protein transport
vesicle docking involved in exocytosis
vesicle fusion
negative regulation of phosphatase activity
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of mucus secretion
protein localization to plasma membrane
synaptic vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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