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          • Primary Antibodies ›
          • SYTL2 Antibodies

          Proteintech

          SYTL2 Polyclonal Antibody

          2 References
          View all (2) SYTL2 antibodies

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          Cite SYTL2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (6)
          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          SYTL2 Antibody (12359-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using (Product # 12359-1-AP) (SYTL2 antibody) at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SYTL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SYTL2 Antibody in Western Blot (WB)
          SYTL2 Antibody in Western Blot (WB)
          SYTL2 Polyclonal Antibody

          Product Details

          12359-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SYTL2 Fusion Protein Ag3023 (7-382 aa encoded by BC015540)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.41 mg/mL

          Amount

          61.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MSKSVPAFL QDESDDRETD TASESSYQLS RHKKSPSSLT NLSSSSGMTS LSSVSGSVMS VYSGDFGNLE VKGNIQFAIE YVESLKELHV FVAQCKDLAA ADVKKQRSDP YVKAYLLPDK GKMGKKKTLV VKKTLNPVYN EILRYKIEKQ ILKTQKLNLS IWHRDTFKRN SFLGEVELDL ETWDWDNKQN KQLRWYPLKR KTAPVALEAE NRGEMKLALQ YVPEPVPGKK LPTTGEVHIW VKECLDLPLL RGSHLNSFVK CTILPDTSRK SRQKTRAVGK TTNPIFNHTM VYDGFRPEDL MEACVELTVW DHYKLTNQFL GGLRIGFGTG KSYGTEVDWM DSTSEEVALW EKMVNSPNTW IEATLPLRML LIAKISK (7-382 aa encoded by BC015540)

          Target Information

          SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Breast cancer-associated antigen SGA-72M; chromosome 11 synaptotagmin; Exophilin-4; protein phosphatase 1, regulatory subunit 151; Synaptotagmin-like protein 2; unnamed protein product

          View more View less

          Gene Aliases: AI266830; CHR11SYT; EXO4; KIAA1597; mKIAA1597; PPP1R151; SGA72M; SLP2; SLP2A; SYTL2

          View more View less

          UniProt ID: (Human) Q9HCH5, (Mouse) Q99N50

          View more View less

          Entrez Gene ID: (Human) 54843, (Rat) 361604, (Mouse) 83671

          View more View less

          Function(s)
          phosphatidylserine binding protein binding phosphatidylinositol-4,5-bisphosphate binding phosphatase binding small GTPase binding neurexin family protein binding Rab GTPase binding calcium ion binding calcium-dependent phospholipid binding syntaxin binding clathrin binding
          Process(es)
          exocytosis intracellular protein transport vesicle docking involved in exocytosis vesicle-mediated transport negative regulation of phosphatase activity synaptic vesicle exocytosis positive regulation of mucus secretion
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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