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Proteintech
SYTL4 Polyclonal Antibody
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Product Details
12128-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYTL4 Fusion Protein Ag2772 (338-671 aa encoded by BC014913)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
39 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IGSMMSIYS EAGDFGNIFV TGRIAFSLKY EQQTQSLVVH VKECHQLAYA DEAKKRSNPY VKTYLLPDKS RQGKRKTSIK RDTVNPLYDE TLRYEIPESL LAQRTLQFSV WHHGRFGRNT FLGEAEIQMD SWKLDKKLDH CLPLHGKISA ESPTGLPSHK GELVVSLKYI PASKTPVGGD RKKSKGGEGG ELQVWIKEAK NLTAAKAGGT SDSFVKGYLL PMRNKASKRK TPVMKKTLNP HYNHTFVYNG VRLEDLQHMC LELTVWDREP LASNDFLGGV RLGVGTGISN GEVVDWMDST GEEVSLWQKM RQYPGSWAEG TLQLRSSMAK QKLGL (338-671 aa encoded by BC014913)
Target Information
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CCB protein; Exophilin-2; Granuphilin; granuphilin b; granuphilin-a; granuphilin-b; synaptotagmin-like 4 (granuphilin-a); Synaptotagmin-like protein 4; unnamed protein product
Gene Aliases: Gph; SLP4; SYTL4
UniProt ID: (Human) Q96C24, (Mouse) Q9R0Q1, (Rat) Q8VHQ7
Entrez Gene ID: (Human) 94121, (Mouse) 27359, (Rat) 140594
intracellular protein transport
exocytosis
synaptic vesicle exocytosis
regulation of calcium ion-dependent exocytosis
positive regulation of exocytosis
negative regulation of insulin secretion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of protein secretion
multivesicular body sorting pathway
plasma membrane repair
insulin secretion
lysosome localization
regulation of plasma membrane repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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