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Proteintech
SYTL5 Polyclonal Antibody
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Product Details
24528-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYTL5 fusion protein Ag21698
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TQQEASRVCV HCHRNLGLIF DRGDPCQACS LRVCRECRVA GPNGSWKCTV CDKIAQLRII TGEWFFEEKA KRFKQVNVLG TDVVRQSILR RSPGAEEVQS QEQTRQDAEK SDTSPVAGKK ASHDGPKRKG FLLSKFRSAT RGEIITPKTD TGRSYSLDLD GQHFRSLKSP PGSDRGSTGS SDLNDQEPGP RTPKSSRSNG VTPGTQSSPA PSTRTVTSVI SREYGFENSM DLAAIEGTSQ ELTKSHRRNT SGTPSIAVSG TSLSSDQSRS ELDLSESFTE DSEDTVSI
Target Information
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: exophilin 9; synaptotagmin 15; synaptotagmin-like 5; Synaptotagmin-like protein 5
Gene Aliases: ENSMUSG00000054453; SLP5; SYTL5
UniProt ID: (Human) Q8TDW5, (Mouse) Q80T23, (Rat) Q812E4
Entrez Gene ID: (Human) 94122, (Mouse) 236643, (Rat) 302538
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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