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          • Primary Antibodies ›
          • SYTL5 Antibodies

          Invitrogen

          SYTL5 Polyclonal Antibody

          View all (4) SYTL5 antibodies

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          Cite SYTL5 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          SYTL5 Antibody in Immunohistochemistry (IHC)
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          SYTL5 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SYTL5 Antibody (PA5-21176) in IHC

          Immunohistochemistry of SYTL2 in rat liver tissue with SYTL5 Polyclonal Antibody (Product # PA5-21176) at 5 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SYTL5 Antibody in Immunohistochemistry (IHC)
          SYTL5 Antibody in Western Blot (WB)
          SYTL5 Polyclonal Antibody

          Product Details

          PA5-21176

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          -

          Immunohistochemistry (IHC)

          5 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A 17 amino acid peptide near the amino terminus of human SYTL5.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11157463

          Product Specific Information

          A suggested positive control is Hela cell lysate.

          PA5-21176 can be used with blocking peptide PEP-1290.

          Target Information

          SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: exophilin 9; synaptotagmin 15; Synaptotagmin-like protein 5

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          Gene Aliases: ENSMUSG00000054453; SLP5; SYTL5

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          UniProt ID: (Human) Q8TDW5, (Mouse) Q80T23, (Rat) Q812E4

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          Entrez Gene ID: (Human) 94122, (Mouse) 236643, (Rat) 302538

          View more View less

          Function(s)
          protein binding phospholipid binding zinc ion binding small GTPase binding neurexin family protein binding metal ion binding calcium ion binding calcium-dependent phospholipid binding Rab GTPase binding syntaxin binding clathrin binding
          Process(es)
          intracellular protein transport exocytosis synaptic vesicle exocytosis regulation of calcium ion-dependent exocytosis calcium ion-regulated exocytosis of neurotransmitter
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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