Search
Bioss
Sarcomeric Alpha Actinin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
BS-10367R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Sarcomeric Alpha Actinin, amino acids 351-450.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This antibody is specific for alpha-skeletal muscle actinin and alpha-cardiac actinin. It stains Z lines and dots in stress fibers of myotubes in skeletal and cardiac muscle but not in non-sarcomeric muscle elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: actinin 1 smooth muscle; alpha actinin 1a; Alpha-actinin cytoskeletal isoform; Alpha-actinin-1; epididymis secretory sperm binding protein; F-actin cross-linking protein; non-muscle alpha-actinin 1; Non-muscle alpha-actinin-1; unnamed protein product
Gene Aliases: 3110023F10Rik; ACTN1; Actn1a; BDPLT15
UniProt ID: (Human) P12814, (Rat) Q9Z1P2, (Mouse) Q7TPR4
Entrez Gene ID: (Human) 87, (Rat) 81634, (Mouse) 109711
transcription coactivator activity
double-stranded RNA binding
actin binding
integrin binding
calcium ion binding
protein binding
cytoskeletal protein binding
vinculin binding
identical protein binding
protein homodimerization activity
ion channel binding
metal ion binding
actin filament binding
structural constituent of postsynapse
protein domain specific binding
ligand-dependent nuclear receptor transcription coactivator activity
focal adhesion assembly
actin filament bundle assembly
negative regulation of cellular component movement
actin crosslink formation
regulation of nucleic acid-templated transcription
cortical cytoskeleton organization
actin filament organization
actin cytoskeleton organization
platelet activation
platelet formation
platelet morphogenesis
regulation of apoptotic process
positive regulation of transcription, DNA-templated
anatomical structure formation involved in morphogenesis
actin filament network formation
muscle cell development
platelet aggregation
postsynapse organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support