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Proteintech
Secretin Polyclonal Antibody
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Product Details
23125-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Secretin Fusion Protein Ag19419 (25-121 aa encoded by BC146571)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ARRHSDGTF TSELSRLREG ARLQRLLQGL VGKRSEQDAE NSMAWTRLSA GLLCPSGSNM PILQAWMPLD GTWSPWLPPG PMVSEPAGAA AEGTLRPR (25-121 aa encoded by BC146571 )
Target Information
Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: prepro-secretin; Secretin
Gene Aliases: SCT
UniProt ID: (Human) P09683
Entrez Gene ID: (Human) 6343
diet induced thermogenesis
adenylate cyclase-activating G-protein coupled receptor signaling pathway
brain development
cellular water homeostasis
hippocampus development
pancreatic juice secretion
response to nutrient levels
regulation of appetite
regulation of synaptic plasticity
embryonic digestive tract development
positive regulation of lipid catabolic process
positive regulation of pancreatic juice secretion
positive regulation of somatostatin secretion
positive regulation of cAMP/PKA signal transduction
negative regulation of gastrin-induced gastric acid secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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