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Secretin Polyclonal Antibody
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Product Details
BS-0088R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Secretin, amino acids 28-54.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prepro-secretin; Secretin
Gene Aliases: SCT; Secr
UniProt ID: (Human) P09683, (Rat) P11384, (Mouse) Q08535
Entrez Gene ID: (Human) 6343, (Rat) 24769, (Mouse) 20287
brain development
visual learning
dentate gyrus development
positive regulation of cAMP biosynthetic process
negative regulation of neuron apoptotic process
embryonic digestive tract development
positive regulation of pancreatic juice secretion
positive regulation of somatostatin secretion
neuronal stem cell population maintenance
negative regulation of gastrin-induced gastric acid secretion
diet induced thermogenesis
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cellular water homeostasis
hippocampus development
pancreatic juice secretion
response to nutrient levels
regulation of appetite
regulation of synaptic plasticity
positive regulation of lipid catabolic process
positive regulation of cAMP/PKA signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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