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Secretogranin III Polyclonal Antibody

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Antibody Testing Data (6)

Secretogranin III Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

Secretogranin III Antibody (10954-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Mouse pancreas tissue slide using (Product # 10954-1-AP) Secretogranin III antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Secretogranin III Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Secretogranin III Antibody in Western Blot (WB)

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Product Details

10954-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:200

Immunocytochemistry (ICC/IF)

View 5 publications 5 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Secretogranin III Fusion Protein Ag1397 (1-468 aa encoded by BC014539)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGFLGTGTW ILVLVLPIQA FPKPGGSQDK SLHNRELSAE RPLNEQIAEA EEDKIKKTYP PENKPGQSNY SFVDNLNLLK AITEKEKIEK ERQSIRSSPL DNKLNVEDVD STKNRKLIDD YDSTKSGLDH KFQDDPDGLH QLDGTPLTAE DIVHKIAARI YEENDRAAFD KIVSKLLNLG LITESQAHTL EDEVAEVLQK LISKEANNYE EDPNKPTSWT ENQAGKIPEK VTPMAAIQDG LAKGENDETV SNTLTLTNGL ERRTKTYSED NFEELQYFPN FYALLKSIDS EKEAKEKETL ITIMKTLIDF VKMMVKYGTI SPEEGVSYLE NLDEMIALQT KNKLEKNATD NISKLFPAPS EKSHEETDST KEEAAKMEKE YGSLKDSTKD DNSNPGGKTD EPKGKTEAYL EAIRKNIEWL KKHDKKGNKE DYDLSKMRDF INKQADAYVE KGILDKEEAE AIKRIYSSL (1-468 aa encoded by BC014539 )

Target Information

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.

The Journal of cell biology

Parchure A,Tian M,Stalder D,Boyer CK,Bearrows SC,Rohli KE,Zhang J,Rivera-Molina F,Ramazanov BR,Mahata SK,Wang Y,Stephens SB,Gershlick DC,von Blume J

Mon Dec 05 00:00:00 EST 2022

Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Lin Z,Li Y,Hang Y,Wang C,Liu B,Li J,Yin L,Jiang X,Du X,Qiao Z,Zhu F,Zhang Z,Zhang Q,Zhou Z

Thu Sep 01 00:00:00 EDT 2022

Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Lin Z,Li Y,Hang Y,Wang C,Liu B,Li J,Yin L,Jiang X,Du X,Qiao Z,Zhu F,Zhang Z,Zhang Q,Zhou Z

Thu Sep 01 00:00:00 EDT 2022

Comparative ligandomics implicates secretogranin III as a disease-restricted angiogenic factor in laser-induced choroidal neovascularization.

The FEBS journal

Ji L,Waduge P,Wan W,Tian H,Li J,Zhang J,Chen R,Li W

Wed Jun 01 00:00:00 EDT 2022

Secretogranin III as a novel target for the therapy of choroidal neovascularization.

Experimental eye research

LeBlanc ME,Wang W,Ji Y,Tian H,Liu D,Zhang X,Li W

Mon Apr 01 00:00:00 EDT 2019

Secretogranin III as a novel target for the therapy of choroidal neovascularization.

Experimental eye research

LeBlanc ME,Wang W,Ji Y,Tian H,Liu D,Zhang X,Li W

Mon Apr 01 00:00:00 EDT 2019

Function-first ligandomics for ocular vascular research and drug target discovery.

Experimental eye research

Rong X,Tian H,Yang L,Li W

Wed May 01 00:00:00 EDT 2019

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.

The Journal of experimental medicine

LeBlanc ME,Wang W,Chen X,Caberoy NB,Guo F,Shen C,Ji Y,Tian H,Wang H,Chen R,Li W

Mon Apr 03 00:00:00 EDT 2017

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.

The Journal of experimental medicine

LeBlanc ME,Wang W,Chen X,Caberoy NB,Guo F,Shen C,Ji Y,Tian H,Wang H,Chen R,Li W

Mon Apr 03 00:00:00 EDT 2017

The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.

Cancer letters

Wang Y,Cui M,Cai X,Sun B,Liu F,Zhang X,Ye L

Wed Oct 01 00:00:00 EDT 2014

The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.

Cancer letters

Wang Y,Cui M,Cai X,Sun B,Liu F,Zhang X,Ye L

Wed Oct 01 00:00:00 EDT 2014

Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.

Brain pathology (Zurich, Switzerland)

Plá V,Paco S,Ghezali G,Ciria V,Pozas E,Ferrer I,Aguado F

Wed May 01 00:00:00 EDT 2013

Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.

Brain pathology (Zurich, Switzerland)

Plá V,Paco S,Ghezali G,Ciria V,Pozas E,Ferrer I,Aguado F

Wed May 01 00:00:00 EDT 2013

Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.

Brain pathology (Zurich, Switzerland)

Plá V,Paco S,Ghezali G,Ciria V,Pozas E,Ferrer I,Aguado F

Wed May 01 00:00:00 EDT 2013

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Cerebral cortex (New York, N.Y. : 1991)

Paco S,Pozas E,Aguado F

Tue Jun 01 00:00:00 EDT 2010

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Cerebral cortex (New York, N.Y. : 1991)

Paco S,Pozas E,Aguado F

Tue Jun 01 00:00:00 EDT 2010

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Cerebral cortex (New York, N.Y. : 1991)

Paco S,Pozas E,Aguado F

Tue Jun 01 00:00:00 EDT 2010

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Cerebral cortex (New York, N.Y. : 1991)

Paco S,Pozas E,Aguado F

Tue Jun 01 00:00:00 EDT 2010

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

The Journal of endocrinology

Hotta K,Hosaka M,Tanabe A,Takeuchi T

Wed Jul 01 00:00:00 EDT 2009

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

The Journal of endocrinology

Hotta K,Hosaka M,Tanabe A,Takeuchi T

Wed Jul 01 00:00:00 EDT 2009

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

The Journal of endocrinology

Hotta K,Hosaka M,Tanabe A,Takeuchi T

Wed Jul 01 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: Secretogranin III; Secretogranin-3; SgIII

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Gene Aliases: 1B1075; AI385542; Chgd; SCG3; SGIII; UNQ2502/PRO5990

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UniProt ID: (Human) Q8WXD2, (Mouse) P47867

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Entrez Gene ID: (Human) 29106, (Mouse) 20255

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Function(s)

poly(A) RNA binding

Process(es)

platelet degranulation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Secretogranin III Polyclonal Antibody

Secretogranin III Antibody (10954-1-AP) in IHC (P)

Product Details

10954-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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