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Separase Polyclonal Antibody
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Product Details
BS-7732R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Separase, amino acids 1851-1950.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Caspase-like protein ESPL1; Cut1/ESP1 related protein; cysteine protease; extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle poles like 1; Extra spindle poles-like 1 protein; FLJ46492; KIAA0165; Separase; Separin; separin, cysteine protease; unnamed protein product
Gene Aliases: AL024103; AU045071; Cerp; ESP1; ESPL1; KIAA0165; PRCE; SEPA; SSE
UniProt ID: (Human) Q14674, (Mouse) P60330
Entrez Gene ID: (Human) 9700, (Mouse) 105988, (Rat) 315330
mitotic sister chromatid segregation
meiotic spindle organization
mitotic cell cycle
nuclear division
mitotic cytokinesis
proteolysis
apoptotic process
chromosome segregation
meiosis I
establishment of mitotic spindle localization
homologous chromosome segregation
positive regulation of mitotic metaphase/anaphase transition
negative regulation of sister chromatid cohesion
mitotic sister chromatid separation
meiotic chromosome separation
nuclear chromosome segregation
mitotic nuclear division
positive regulation of mitotic sister chromatid separation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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