This antibody is predicted to react with bovine, canine, equine, mouse, porcine and rat based on sequence homology.
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
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Protein Aliases: CDC10; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 cell division cycle 10 homolog; CDC10 protein homolog; CDC3; cell division cycle 10; Nbla02942; SEPT7; SEPT7A; septin 7; septin 7 variant 4; Septin-7
Gene Aliases: CDC10; CDC3; NBLA02942; SEPT7; SEPT7A; SEPTIN7
UniProt ID: (Human) Q16181
Entrez Gene ID: (Human) 989