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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Sigma-1 Receptor Antibodies

          Invitrogen

          Sigma-1 Receptor Polyclonal Antibody

          View all (11) Sigma-1 Receptor antibodies

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          Cite Sigma-1 Receptor Polyclonal Antibody

          • Antibody Testing Data (4)
          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          Sigma-1 Receptor Antibody (PA5-141020) in IHC (P)

          Immunohistochemistry analysis of Sigma1-receptor in paraffin-embedded human placenta tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 1% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with Sigma1-receptor Polyclonal antibody (Product # PA5-141020) using a dilution of 1... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Sigma-1 Receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Sigma-1 Receptor Antibody in Western Blot (WB)
          Sigma-1 Receptor Polyclonal Antibody

          Product Details

          PA5-141020

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:600-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein within human Sigma1-receptor aa 74-223.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.4, with 50% glycerol, 0.2% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2932472

          Target Information

          This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Aging-associated gene 8 protein; AL024364; mSigmaR1; opioid receptor, sigma 1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; Sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; Sigma-1 Receptor; sigma1 receptor; Sigma1-receptor; SR BP; SR-BP; SR31747 binding protein 1; SR31747-binding protein

          View more View less

          Gene Aliases: AAG8; ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SIGMAR1; SR-BP; SR-BP1; SRBP

          View more View less

          UniProt ID: (Human) Q99720, (Mouse) O55242

          View more View less

          Entrez Gene ID: (Human) 10280, (Mouse) 18391

          View more View less

          Function(s)
          opioid receptor activity drug binding receptor activity protein binding transmembrane signal receptor
          Process(es)
          lipid transport nervous system development opioid receptor signaling pathway regulation of neuron apoptotic process protein homotrimerization transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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